Portrait

Somayeh Saghamanesh

I am a Marie Skłodowska-Curie Action (MSCA) postdoctoral fellow at the Center for X-ray Anlaytics (CXA) at Empa. My background is medical physics and biomedical engineer, interested in a wide range of biomedical topics. My main research interests are the development of advanced medical imaging (X-ray radio/mammography, CT, MRI, PET/SPECT, hybrid nuclear medicine, …) and radiotherapy (IMRT, IGRT, VMAT, brachytherapy, …) technologies, image processing and reconstruction, and Radiomics analysis.

Currently, I am active in following research projects:

  • As my European Horizon 2020 project, I work on the development of multimodal X-ray imaging and tomography techniques (hardware and software) for precision medicine. In our center, I have developed an add-on laboratory-based X-ray speckle based imaging (SBI) system and a virtual simulator framework for research and system optimization. We are investigating various potential biomedical applications for the developed system, e.g. for scanning urinary stones and detecting the distribution of gold nanoparticles inside biological tissues. In addition, we are also working on industrial applications, e.g., dynamic imaging for characterization of macro-porous and mesoporous materials. We hope this opens a room for further studies and transferring such multimodal imaging to preclinical/clinical and industrial practices.
  • Together with our partners in University Hospital of Geneva (HUG), I work on a SNF-funded project about the image analysis of thrombus from stroke patients through propagation-based X-ray phase-contrast microtomography.
  • As a collaboration with international and clinical partners, I investigate the enhancement of embedded calculation algorithms for treatment planning systems (TPS) in the image-guided radiation therapy (IGRT) modality.

X-ray propagation-based microtomography of thrombus from stroke patients (pdf)

X-ray speckle-based dark-field imaging of water transport in porous ceramics (video)

 

Memberships:

American Association of Physicists in Medicine (AAPM)

Iranian Association of Medical Physicists (IAMP)

Swiss Society for Optics and Microscopy (SSOM)