Studying cell behaviour on prospective implant surfaces describes the surface cytocompatibility and gives an initial indication as to the appropriateness for fracture repair applications. With long term or permanent osteosynthesis implants osseointegration is vital to their success. Early soft tissue integration without liquid filled capsule formation and good vascularisation is necessary at the implant / tissue interface, especially for deterrence of infection. In certain cases such as distal radius fractures where tendons have to glide over internal fixation plates, tissue adhesion is undesirable since this prevents normal tissue motion.

Microtopography is one of the primary factors controlling cell adhesion and can be used simply to control this. The aim of this talk will be to illustrate with some simple examples of controlling tissue adhesion to surfaces which function both in vitro and are able to withstand the harsh in vivo surroundings.

Vortragssprache: englisch